EMBO Workshop: Glycobiology & Glycochemistry: Applications to human health and disease

Presentation

Very recently, Glycosciences become vibrant, expanding the knowledge of modern molecular biology and medicine. A long last, the importance of glycans in biological processes starts being appreciated and Glycosciences commence to provide solutions and offer tools for demanding health problems.
Glycobiology and Glycochemistry are two main and intermeshed areas of Glycosciences, dealing with various aspects of glycans, including carbohydrate structure, biochemistry, biological functions and applications.
The EMBO Workshop “Glycobiology & Glycochemistry: Applications to human health and disease” aims to foment the creation of “scientifically bilingual” investigators fluent in glycan chemistry and biology. These characteristics will sustain and advance the identification of key glycobiological aspects, its alterations in diseases, and the application of Glycans and Glycoengineering strategies in the design of novel therapies. It is an exciting time for Glycosciences! Time where important glycan-based biomarkers are emerging, and a great potential for the development of groundbreaking applications with new glycan-based therapeutics is foreseen to improve human health.

Course Aims

This Glycobiology and Glycochemistry Workshop is one of the first dedicated to reveal the translation of Glycosciences to the improvement of human health.

It intends to bring together two main areas of Glycosciences, Glycobiology and Glycochemistry, and to foment the knowledge on the structure of “glycomaterials” and how they participate in different biological processes, controlling disease, and preserving human health. The Workshop aims to contribute for the creation of cadres of “scientifically bilingual” investigators fluent in glycan chemistry and glycan biology.
At the end of this Workshop, the learners should be able to discuss distinct scientific subjects within the scope of Glycosciences.
Themes
Glycochemistry
Glycans in human physiological mechanisms
Glycans and Cancer
Congenital Disorders of Glycosylation
Biosynthesis of disease related carbohydrate antigens
Methods in Glycosciences

Programme

Date

Time

Speaker/session title/lunch

Saturday May 24

12:00 – 15:00

Registration

 

15:00 – 16:00

Poster sneak preview

 

16:00 – 17:00

Paula Videira/ OPENING LECTURE “Opening Introduction and Course Overview”

 

17:00 – 18:00

Amélia Pilar Rauter

 

18:00 – 19:00

Anne Dell/ Keynote lecturer

 

19:00 – 19:30

“Course details, overview of syllabus and evaluation. Presentation of the work groups and distribution of the themes”

 

 

 

Sunday May 25

 

Session: Glycochemistry

 

9.00 – 10:00

LECTURE Serge Perez

 

10:00 – 10:30

Coffee Break

 

10:30 – 11:30

LECTURE

 

12:30 – 14:30

Lunch

 

 

Session: Biosynthesis of disease related carbohydrate antigens

 

14:00 – 15:00

LECTURE Stefan Oscarson

 

15:00 – 16:00

Poster Session

 

16:00 – 16:30

Coffee Break

 

16:30 – 19:00

Work Groups /Tutorials

Monday May 26

 

 

Session: Glycans in human physiological mechanisms

 

9.00 – 10:00

LECTURE Joseph Lau

 

10:00 – 10:30

Coffee Break

 

10:30 – 11:30

LECTURE – Paula Videira

 

 

Session: Glycans and Cancer

 

11:30 – 12:30

LECTURE – Fabio Dall’Olio

 

12:30 – 14:30

Lunch students and speakers

 

14:30 – 15:30

LECTURE – Marco Trinchera

 

15:30 – 16:30

Poster Session

 

16:30 – 17:00

Coffee Break

 

17:00 – 18:00

Oral Presentation from selected abstracts from young investigators (10 minutes + 5 minutes discussion)

Tuesday May 27

 

 

 

 

Session: Congenital Disorders of Glycosylation

 

9.00 – 10:00

LECTURE / Dirk Lefeber

 

10:00 – 10:30

Coffee Break

 

10:30 – 11:30

PRATICAL CASES/ Dirk Lefeber

 

11:30 – 12:30

Round table/ Discussion

 

12:30 – 14:00

Lunch

 

14:00 – 16:00

LECTURE

 

16:00 – 16:30

Coffee Break

 

16:30 – 17:30

Group Discussions

 

17:30 – 18:30

Oral Presentation of selected abstracts from young researchers/ Posters (10 minutes + 5 minutes discussion)

 

18:30 - 19:30

Meetings between students and teachers

Wednesday May 28

 

 

 

 

Session: Methods in Glycosciences

 

9.00 – 10:00

LECTURE  Angelina Palma

 

10:00 – 10:30

Coffee Break

 

10:30 – 11:30

LECTURE

 

11:30 – 12:30

LECTURE  Ferreira, Alexandre

 

12:30 – 14:00

Lunch

 

14:00 – 16:00

Group Presentations and Discussions

 

16:00 – 16:30

Coffee Break

 

16:30– 18:30

Group Presentations and Discussions

 

 

COLLOQUIUM - Conclusive Thoughts and final Discussion, distribution of certificates

Lectures:
The Workshop includes easy-to-understand lectures, provided by scientists and professors very well renown in Glycosciences. Lectures are focused on the current overview of the fundamental facts, concepts, methods and applications in Glycosciences. The lectures aim to encourage discussion and further research in Glycosciences, by revealing the complex involvement of glycans in distinct human-related physiological and pathological conditions. An e-learning platform with video recorded lectures will also be available for students to get in depth information about Glycobiology and Glycochemistry.
Selected Presentations:
The Workshop includes Oral presentations (10 minutes + 5 minutes discussion) from earlier stage researchers, and students to provide the chance to show results. Ample time is provided for discussions both formally after the presentations but also in an informal atmosphere during the workshop.
Posters:
Sufficient space and time for a poster session is planned. It includes one hour of Poster sneak preview, and two poster sessions (one hour each). The posters will be available for viewing throughout the entire meeting and all posters will be displayed in one room. Participants may display ‘virtual posters’ (e.g. live demonstration of research on presenter's laptop).
Workgroups:
Participants (a maximum of 8) will be asked to discuss a research article, in group, prepare a small presentation to be presented at the end of the Workshop for all the audience. The presentations will be supervised by teachers and evaluated also by all other participants from other groups. The articles will be related with Glycosciences and in most cases from teachers also participating in the Workshop
Social events:
Different social event will be incorporated during the event:
-Wellcome drinks and snacks
-Walking in Lisbon downtown /sunset over the Tagus river
-Gala Dinner with Fado, a moment of Portuguese culture.
In addition, the Workshop includes all meals to foment the get together and social environment.

How discussion and collaborations between participants will be stimulated?
Besides the poster sections and oral presentations that give participants a great opportunity to present their work, the Workshop also includes other activities to stimulate participation of all attendees:
- There will be Workgroups, where participants (a maximum of 8) will be asked to discuss a research article, in group, prepare a small presentation to be presented at the end of the Workshop for all the audience. The presentations will be supervised by teachers and evaluated also by all other participants from other groups. The articles will be related with Glycosciences and in most cases from teachers also participating in the Workshop.
- The participants will have the chance to select a teacher to share a table at lunch time.
- Participants will be encouraged to approach speakers in public and there will be a time where they may request private meetings with teachers.
- A poster quiz game and prize will be held to promote interaction between poster presenters and all participants.

Types of Assessment Methods

The students will be selected all over the world based on the topics and originality of the abstract that is submitted. The selection is intended also to form a balanced panel of chemists and biologists, which also includes medical, pharmacologists, and other students. Nine participants will be selected for oral presentations. Participants will be organized in groups and asked to discuss a research article, in group. A presentation will be presented at the end of the Workshop for all the audience. The presentations will be supervised and evaluated by teachers.
In order to be certificated, participants have to participate in all sessions and actively participate in the Group presentations.

Teaching staff

Name

Institution

Country

Alexandre Ferreira

Institute of Oncology of Porto

Portugal

Amélia Pilar Rauter

The Faculty of Sciences of the University of Lisbon

Portugal

Angelina Palma

Nova University of Lisbon

Portugal

Anne Dell

Imperial College

London - UK

Antoni Planas

Universitat Ramon Llull

Spain

Catherine Ronin

SiaMed'Xpress Université

France

Dirk Lefeber

Radboud University Nijmegen Medical Centre

The Netherlands

Fabio Dall'Olio

Faculty of Medicine Bologna University

Italy

Laura Cipolla

University of Milano-Bicocca

Italy

Marco Trinchera

The University of Insubria

Italy

Michaela Wimmerova

Central European Institute of Technology

Czech Republic

Paula Videira

Nova University of Lisbon

Portugal

Serge Perez

Centre de Recherches sur les Macromolécules Végétales

France

Stefan Oscarson

University College Dublin

Ireland

Entry Requirements

The course is designed to train pre- and post-doctoral scientists, within areas related with Chemistry or Biology. It also includes physicians and educators interested in furthering Glycosciences: This course aims to build upon and compliment the participant’s previous knowledge of chemistry, molecular and cellular biology.

Admission criteria

The students will be selected all over the world based on the topics and originality of the abstract that is submitted. The selection will be made by the organizers and Scientific committee and it is intended also to form a balanced panel of chemists and biologists, which also includes medical, pharmacologists, and other students.

Information and Registration

Universidade NOVA de Lisboa
Faculdade de Ciências Médicas
Divisão Académica - Secção de Pós-Graduação
Campo Mártires da Pátria, 130 · 1169-056 Lisboa - Portugal
Tel. +351 21 880 30 66 · Fax +351 21 880 30 68
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